Price loading...

Cytochrome P450: In Vitro Methods and Protocols (Methods in Pharmacology and Toxicology)

Pharmacy - Dispensing

Price data last checked 131 day(s) ago - refreshing...

View at Amazon

Price History & Forecast

No Price Data Available

Price history will appear here once data is collected from Amazon.

Price Distribution

No price data available for histogram

Description

This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels, kinetic parameters for individual CYP enzymes, CYP inhibition and induction, time-dependent inhibition (TDI), CYP stability, non-CYP stability, UDP-glucuronosyltransferases (UGT) stability, excretion mechanisms, and drug-drug interactions (DDI), all addressed in this volume. Written for the Methods in Pharmacology and Toxicology series, chapters include helpful background information on the in vitro assay, a list of all the materials, reagents, and equipment necessary to carry out the assay, a step-by-step protocol, notes containing common and unexpected experimental problems in the assay, as well as references containing important supplementary reading. Authoritativeand practical, Cytochrome P450: In Vitro Methods and Protocols serves as a key guide for researchers in the area of discovery and development of new medicines.

Product Specifications

Format: paperback
ASIN: 1071615440
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Allied Health Professions > Pharmacy - Dispensing
Domain: Amazon UK
Release Date: 10 July 2022
Listed Since: 13 June 2022

Barcode

No barcode data available

Cytochrome P450: In Vitro Methods and Protocols (Methods in Pharmacology and Toxicology)

Price History & Forecast

No Price Data Available

Price Distribution

Description

Product Specifications

Barcode

Similar Products You Might Like

Humana Cytochrome P450: In Vitro Methods and Protocols Book

Humana Optimization in Drug Discovery: In Vitro Methods Book

Optimization in Drug Discovery: In Vitro Methods (Methods in Pharmacology and Toxicology)

Cytochrome P450 Protocols: 987 (Methods in Molecular Biology, 987)

Humana Cytochrome P450 Protocols: 320 - Methods in Molecular Biology

Drug Metabolism and Transport: Molecular Methods and Mechanisms (Methods in Pharmacology and Toxicology)

Cytochrome P450 Protocols: 320 (Methods in Molecular Biology, 320)

ADVANCED SEMICONDUCTING MATERIALS AND D: Biochemistry, Pharmacology & Health Implications (Biochemistry Research Trends)

Optimization in Drug Discovery (Methods in Pharmacology and Toxicology)

Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery and Development

Cytochrome P-450: Structure, Mechanism, and Biochemistry

Methods for Stability Testing of Pharmaceuticals (Methods in Pharmacology and Toxicology)

Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary: Volume 95 (Advances in Pharmacology, Volume 95)

Cytochrome P450: Structure, Mechanism, and Biochemistry

The Handbook of Metabolomics: 17 (Methods in Pharmacology and Toxicology)

Protocols in In Vitro Hepatocyte Research: 1250 (Methods in Molecular Biology, 1250)

Apoptosis Methods in Toxicology (Methods in Pharmacology and Toxicology)

In Vitro Toxicology Systems (Methods in Pharmacology and Toxicology)

Cytochrome P450: Structure, Mechanism, and Biochemistry

Stem Cell-Derived Models in Toxicology (Methods in Pharmacology and Toxicology)

Evaluation of Drug Candidates for Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology (Wiley Series in Drug Discovery and Development)

Drug Metabolism in Drug Design and Development: Basic Concepts and Practice

Interindividual Variability in Human Drug Metabolism: Variability in Drug Metabolism

Guanylate Cyclase and Cyclic GMP: Methods and Protocols: 1020 (Methods in Molecular Biology, 1020)