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Humana Optimization in Drug Discovery: In Vitro Methods Book

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Description

Optimization in Drug Discovery: In Vitro Methods, Second Edition, provides a comprehensive guide for professionals in pharmacology and toxicology. This thoroughly revised and updated text covers a wide spectrum of essential in vitro assays required for modern drug development processes. Readers can access detailed information on formulation, plasma binding, absorption, and permeability. The book also explores critical metabolic processes, including cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, alongside CYP inhibition and induction studies. This volume is part of the Methods in Pharmacology and Toxicology series. It serves as a technical resource for understanding drug transporters, drug-drug interactions through reactive metabolite assessment, genotoxicity, and both chemical and photo-mutagenicity assays. It is an essential reference for those working in medical and healthcare research environments.

Key Features

Covers a wide spectrum of in vitro assays including formulation, plasma binding, absorption, and permeability.

Provides detailed technical information on cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism.

Includes essential studies on CYP inhibition, induction, and various drug transporter mechanisms.

Assesses drug-drug interactions via the study of reactive metabolites.

Contains specialized sections on genotoxicity and both chemical and photo-mutagenicity assays.

Part of the professional Methods in Pharmacology and Toxicology series for researchers.

Product Specifications

Brand
Humana
Format
paperback
Domain
Amazon UK
Release Date
23 August 2016
Listed Since
11 August 2016

Barcode

No barcode data available

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