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Humana Drug Metabolism and Transport: Molecular Methods and Mechanisms (Methods in Pharmacology and Toxicology)

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Description

A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.

Product Specifications

Brand
Humana
Format
Hardcover
Domain
Amazon UK
Release Date
24 September 2004
Listed Since
05 February 2007

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