THIOSEMICARBAZONE IRON CHELATOR: Evaluation of the anti-cancer activity and mechanisms of action - Image 1

£71.00

It has never been this cheap. We have no record of a lower price.

£71 today · cheaper than every other day in the last 3 months

LAP Lambert Academic Publishing THIOSEMICARBAZONE IRON CHELATOR: Evaluation of the anti-cancer activity and mechanisms of action

Name: THIOSEMICARBAZONE IRON CHELATOR: Evaluation of the anti-cancer activity and mechanisms of action
Brand: LAP Lambert Academic Publishing
Price: 71.0 GBP
Availability: InStock

Medical & Healthcare Practitioners

Price data last checked 34 day(s) ago - refreshing...

View at Amazon

We'll watch every seller, every day. One email when your price arrives.

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 57 days · 57 data points (no recent data)

Historical

Generating forecast…

View at Amazon ↗

Medical & Healthcare Practitioners

Price data last checked 34 day(s) ago - refreshing...

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↑ Price chart
when this has been cheap or pricey

↑ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price Distribution

Price distribution over 57 days • 1 price levels

Days at Price

Price Analysis

Most common price: £71 (57 days, 100.0%)

Price range: £71 - £71

Price levels: 1 different prices over 57 days

Description

Previous studies demonstrated that thiosemicarbazone iron chelator possessed potent and selective anti-cancer activity. In this study, the in vitro and in vivo anti-tumor efficacy and tolerability of 2-benzoylpyridine thiosemicarbazone (BpT) iron chelators were examined. The BpT chelators were tested against human lung cancer cells in vitro and tumor xenografts in mice. The toxicity of Bp44mT and its effects on the expression of iron-regulated molecules involved in growth and cell cycle control were investigated. The results shown demonstrate the anti-tumor activity of the orally-active Bp44mT chelator, which was well tolerated in vivo. Furthermore, the cytotoxicity of thiosemicarbazones is likely to be mediated, in part, through their redox activity and effects on multiple thiol-containing systems. In terms of signal transduction, iron chelation may influence the MAPK signaling pathways via the thioredoxin-ASK1 signalosome. These results emphasize the importance of redox-activity of thiosemicarbazone chelators. Considering their potent anti-tumor activity, these investigations facilitate the future development of promising thiosemicarbazone iron chelators as anti-cancer agents.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 3844386769
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners
Domain: Amazon UK
Release Date: 03 July 2011
Listed Since: 06 July 2011

Barcode

No barcode data available

It has never been this cheap. We have no record of a lower price.

LAP Lambert Academic Publishing THIOSEMICARBAZONE IRON CHELATOR: Evaluation of the anti-cancer activity and mechanisms of action

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Gold And Platinum Complexes Of Anticancer Drug Derivatives: Anticancer Drug Derivatives

Metal-Binding Drugs for Cancer Therapy: Drug Delivery and Membrane Transport of Thiosemicarbazones

Cancer Chemotherapy: Concepts, Clinical Investigations and Therapeutic Advances: 42 (Cancer Treatment and Research, 42)

Pancratistatin: An Apoptosis Inducer: Applications to Cancer Therapy

Synthesis of Some Novel Bioactive Indoles as Anticancer Agents: Bioactive Indoles

SYNTHESIS OF (-) – PYRENOPHOROL, ANTICANCER EVALUATION OF HETEROCYCLES: SYNTHESIS OF (-) – PYRENOPHOROL, AND ANTI-CANCER EVALUATION OF BENZIMIDAZOLE, BENZTHIAZOLE AND SULFONAMIDE DERIVATIVES

COMPUTATIONAL ASSESSMENT OF DIFFERENT CANCER CONTROLLING DRUGS: Pharmacological & Toxicological Assessment through an In Silico Approach

Pyrazoles and Pyrrolo[3,2-c]pyridines as Anticancer Agents: Novel Pyrazoles and Pyrrolo[3,2-c]pyridines as Potential Anticancer Agents

An altranative approach for treatment of cancer: A preliminary study: Interaction of anticancer drugs with divalent metal Cu (II); An in vitro study

Design and Synthesis of New Thiazole Derivatives as Anticancer Agents: p56 Lck Inhibitors

A Study on Some Natural Products with Potential Anticancer Activity: Phytochemical Study of Natural Anticancer Agents

Fitoekdisteroidy v lechenii gnoynykh zabolevaniy legkikh i plevry

Synthesis, Antioxidant and Antimicrobial Activity of New Thiophene: Thiophene containing antimicrobial and antioxidant compound

Bioactive Semicarbazones and their metal Synergy: Synthesis, biological applications and theoreticalinvestigation of novel organic and inorganic compounds

Chemosensitivity Testing in Oncology: 161 (Recent Results in Cancer Research, 161)

New Purine Nucleosides in Cancer Chemotherapy

Adverse drug reactions due to cancer chemotherapy: Adverse drug reactions due to cancer chemotherapy in a tertiary care centre

Biological Important of Thiazole Derivatives: Preparation, Characterization and Antimicrobial Studies of Novel Thiazole Derivatives

Arsenic-induced reproductive and metabolic toxicity in mice:: Protective role of thiol compounds

Anti-cancer effects of α-mangostin on human breast cancer cell lines

Pyrazolopyrimidine derivatives as cyclin-dependant kinase inhibitors

Synthesis of benzothiazoles with anticipated biological activity: Synthetic applications of cyanoacetamide moiety incorporated benzothiazole ring system

Organ Directed Toxicities of Anticancer Drugs: Proceedings of the First International Symposium on the Organ Directed Toxicities of the Anticancer ... 4–6, 1987: 53 (Developments in Oncology, 53)

It has never been this cheap. We have no record of a lower price.

LAP Lambert Academic Publishing THIOSEMICARBAZONE IRON CHELATOR: Evaluation of the anti-cancer activity and mechanisms of action

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Gold And Platinum Complexes Of Anticancer Drug Derivatives: Anticancer Drug Derivatives

Metal-Binding Drugs for Cancer Therapy: Drug Delivery and Membrane Transport of Thiosemicarbazones

Cancer Chemotherapy: Concepts, Clinical Investigations and Therapeutic Advances: 42 (Cancer Treatment and Research, 42)

Pancratistatin: An Apoptosis Inducer: Applications to Cancer Therapy

Synthesis of Some Novel Bioactive Indoles as Anticancer Agents: Bioactive Indoles

SYNTHESIS OF (-) – PYRENOPHOROL, ANTICANCER EVALUATION OF HETEROCYCLES: SYNTHESIS OF (-) – PYRENOPHOROL, AND ANTI-CANCER EVALUATION OF BENZIMIDAZOLE, BENZTHIAZOLE AND SULFONAMIDE DERIVATIVES

COMPUTATIONAL ASSESSMENT OF DIFFERENT CANCER CONTROLLING DRUGS: Pharmacological & Toxicological Assessment through an In Silico Approach

Pyrazoles and Pyrrolo[3,2-c]pyridines as Anticancer Agents: Novel Pyrazoles and Pyrrolo[3,2-c]pyridines as Potential Anticancer Agents

An altranative approach for treatment of cancer: A preliminary study: Interaction of anticancer drugs with divalent metal Cu (II); An in vitro study

Design and Synthesis of New Thiazole Derivatives as Anticancer Agents: p56 Lck Inhibitors

A Study on Some Natural Products with Potential Anticancer Activity: Phytochemical Study of Natural Anticancer Agents

Fitoekdisteroidy v lechenii gnoynykh zabolevaniy legkikh i plevry

Synthesis, Antioxidant and Antimicrobial Activity of New Thiophene: Thiophene containing antimicrobial and antioxidant compound

Bioactive Semicarbazones and their metal Synergy: Synthesis, biological applications and theoreticalinvestigation of novel organic and inorganic compounds

Chemosensitivity Testing in Oncology: 161 (Recent Results in Cancer Research, 161)

New Purine Nucleosides in Cancer Chemotherapy

Adverse drug reactions due to cancer chemotherapy: Adverse drug reactions due to cancer chemotherapy in a tertiary care centre

Biological Important of Thiazole Derivatives: Preparation, Characterization and Antimicrobial Studies of Novel Thiazole Derivatives

Arsenic-induced reproductive and metabolic toxicity in mice:: Protective role of thiol compounds

Anti-cancer effects of α-mangostin on human breast cancer cell lines

Pyrazolopyrimidine derivatives as cyclin-dependant kinase inhibitors

Synthesis of benzothiazoles with anticipated biological activity: Synthetic applications of cyanoacetamide moiety incorporated benzothiazole ring system

Organ Directed Toxicities of Anticancer Drugs: Proceedings of the First International Symposium on the Organ Directed Toxicities of the Anticancer ... 4–6, 1987: 53 (Developments in Oncology, 53)