Anti-cancer effects of α-mangostin on human breast cancer cell lines - Image 1

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LAP Lambert Academic Publishing Anti-cancer effects of α-mangostin on human breast cancer cell lines

Name: Anti-cancer effects of -mangostin on human breast cancer cell lines
Brand: LAP Lambert Academic Publishing
Price: 46.0 GBP
Availability: InStock

Pharmacology

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Description

In this book, α-mangostin (AM), a xanthone compound was investigated for its apoptosis mechanism on MCF-7 and MDA-MB-231 cell lines. The treatment of the cells with AM prompted apoptosis with cell death-transducing signals. This type of apoptosis was suggested to occur through the both extrinsic and intrinsic pathways and prevention of translocation of NF-κB from the cytoplasm to the nucleus. Our results revealed AM prompt apoptosis of the both cells through NF-κB, Bax/Bcl-2 and HSP70 protein modulation with the contribution of caspases. Therefore, AM is deemed to have considerable potential in the control of breast cancer.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 3659799157
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine > Pharmacology
Domain: Amazon UK
Release Date: 10 November 2015
Listed Since: 04 December 2015

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LAP Lambert Academic Publishing Anti-cancer effects of α-mangostin on human breast cancer cell lines

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