RAS Drug Discovery: Past, Present and Future - Image 1

£132.51

Elsevier RAS Drug Discovery: Past, Present and Future

Name: RAS Drug Discovery: Past, Present and Future
Brand: Elsevier
Price: 132.51 GBP
Availability: InStock

Biochemistry

About as cheap as it gets. The only time it was cheaper was 7 months ago.

£133 today · all-time low £129 (Oct 2025) · usually the usual

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Description

KRAS Drug Discovery: Past, Present and Future is a comprehensive overview of the state-of-the-art medicinal chemistry approaches towards targeting the formerly undruggable oncogene, KRAS. It includes Seminal medicinal chemistry case histories of KRASG12C inhibitors such as Sotorosib, the first approved KRASG12C inhibitor for NSCLC, alongside the latest advances towards identification of in vivo tools and development candidates targeting KRAS G12D, KRAS G13C and other mutations. The book also provides the reader with a comprehensive overview of the in vitro assay systems, in vivo pharmacology xenograft models and chemical biology tools available to characterize small molecule inhibitors of KRAS. Highlights key structure-based drug design (SBDD) innovations to generate potency and selectivity vs. KRAS Analyzes medicinal chemistry case histories for seminal contributions to the KRAS field Provides an overview of in vitro and in vivo methods for drugging KRAS

Product Specifications

Brand: Elsevier
Format: Paperback
ASIN: 0443218617
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biochemistry
Domain: Amazon UK
Release Date: 01 November 2024
Listed Since: 08 March 2024

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Elsevier RAS Drug Discovery: Past, Present and Future

About as cheap as it gets. The only time it was cheaper was 7 months ago.

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