Humana Lung Cancer: Volume 2: Diagnostic and Therapeutic Methods and Reviews: 75 (Methods in Molecular Medicine, 75)

This work, Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews, in the Methods in Molecular Medicine series presents an overview of the current status of those methods useful in the diagnosis and tre- ment of lung cancer―both as it exists in the clinic and as it is being revoluti- ized in the laboratory. The book is intended to serve as a resource for researchers wishing to increase their knowledge of current and cutting edge technologies, in order that their investigations into neoplasms of the lung may benefit from this enriched diversity of techniques and approaches. Owing to the complex nature of the disease and the variety of methods available to analyze and attack it, no volume attempting to define diagnostic and therapeutic approaches to lung cancer can ever be complete. The sheer number of investigators involved in lung cancer research guarantees that some aspect will be inadvertently excluded. However, I hope that the range of techniques included herein will serve to open up new avenues of investigation for both the novice and experienced researcher. Review "This is a good compilation of scientific information on lung cancer...it serves as a useful resource for scientists involved in lung cancer." -Doody's Health Sciences Book Review Journal "The strongest part of the book is the detailed description of the different molecular techniques for marker analyses, which will be of great value for the lung cancer scientists working in basic science ant translational lung cancer research." -Annals of Oncology From the Back Cover Molecular-based laboratory methods can help significantly in the diagnosis and treatment of lung cancer, a leading cause of death worldwide. In Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews, leading physicians, scientists, and noted researchers describe step-by-step techniques for lung cancer diagnosis based on the molecular analysis of clinical samples. These experts review currently accepted treatments and outline a variety of novel therapies, including treatments based on gene therapy, immunotherapy, and chemoprevention, and show how these newly improved techniques can give a better appreciation of the prognosis associated with the particular mutation uncovered by the technique. These methods use a variety of molecular techniques, including the manipulation of gene expression and the alteration of immune status, to combat lung cancer. A companion volume, Lung Cancer, Volume 1: Molecular Pathology Methods and Reviews, illuminates the etiology of lung cancer and provides reliable techniques for detecting the responsible genetic mutations at the cellular, DNA, and protein levels. Comprehensive and informative, Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews illuminates how molecular approaches can and are being applied to the diagnosis of lung cancer. Together, these two volumes constitute an unprecedented resource for those who wish to better understand how this disease is being diagnosed and treated, and what novel techniques may be available to improve both processes.