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Humana Cancer Drug Resistance (Cancer Drug Discovery and Development)

Name: Cancer Drug Resistance (Cancer Drug Discovery and Development)
Brand: Humana

5396908

Oncology

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Description

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

Product Specifications

Brand: Humana
Model: 5396908
Format: hardcover
ASIN: 1588295303
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain: Amazon UK
Release Date: 09 March 2006
Listed Since: 05 February 2007

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Humana Cancer Drug Resistance (Cancer Drug Discovery and Development)

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