Academic Press Antimicrobial Peptides: Challenges and Future Perspectives

Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides. Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development. Review Bridges the gap between reported peptide antibiotics and their therapeutic applications From the Back Cover <i>Antimicrobial Peptides: Discovery to Drug Development</i> covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided in to 16 chapters that are arranged in a sequence and preceded by chapters on historical developments and role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization in detail suitable for interdisciplinary research. Chapters from 5 to 10 provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. The marine ecosystem being one of the excellent sources of unexplored peptides, chapter 11 broadens readers understanding on marine based antimicrobial peptides. This is followed by an informative overview on peptides with antiviral properties and those targeting multi drug resistant bacteria. Additionally, recent reports and mechanism on resistance against antimicrobial peptides are provided. Key insights in to challenges and future perspectives of peptide drug development have been extensively covered in the end chapters. <i>Antimicrobial Peptides: Discovery to Drug Development</i> is an invaluable reference and essential reading for bioscience students, researchers and industrialists. About the Author He has completed his masters in Microbiology from Kuvempu University, Karnataka, India and received PhD in Microbiology from Kannur University, Kerala India. His area of research is peptide antibiotics, biofilms, drug resistance and Phage therapy. He has more than five years of teaching and research experience. His contribution in antimicrobial peptides and drug resistance appeared in various journals including-peptides, Journal of Applied microbiology, Applied Biochemistry & Biotechnology, Mycopathologia. He has been Board of studies member in Microbiology (2014-18) and Chairman, Board of Examiners in Biotechnology and Microbiology (2012-15), Kannur University. He is a reviewer of Journal of Bacteriology and Mycology. He is a member of Indian Peptide Society (IPS), Indian Initiative for Management of Antibiotic Resistance (IIMAR) and International Society for Viruses of Microorganisms (ISVM). He is also the Research Director of Kannur University since 2018. Dr. Sreejith has received MPhil in Biophysics and PhD in Biochemistry from Mahatma Gandhi University, Kerala, India. He has more than 19 years of teaching and research experience. His area of research is antimicrobial peptides and proteins, anti inflammatory compounds and cancer biology. Since 2008, his team has contributed extensively in the aforementioned area with publications appearing in the Journal of Applied Microbiology, Applied Biochemistry and Biot