Springer Type IV Secretion in Gram-Negative and Gram-Positive Bacteria: 413 (Current Topics in Microbiology and Immunology, 413)

Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians. From the Back Cover Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians. About the Author Prof. Dr. rer. nat. Steffen Backert Chair of Microbiology Friedrich Alexander University Erlangen/Nuremberg Department of BiologyDivision of MicrobiologyStaudtstr. 5D-91058 ErlangenGermanyTel.  ++49 9131 8528081Fax  ++49 9131 8528082  Prof. Dr. techn. Elisabeth GrohmannProfessor of MicrobiologyBeuth University of Applied Sciences BerlinDepartment of Life Sciences and TechnologyDivision of MicrobiologyForum SeestraßeSeestr. 64D-13347 BerlinGermanyTel. ++49 30 45043942Fax ++49 30 45043983