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Springer Proteostasis and Disease: Mechanisms to Clinical Applications

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Description

Proteostasis and Disease offers a comprehensive exploration of protein homeostasis in health and disease, compiled by leading researchers from the European PROTEOSTASIS network. This volume examines the fundamental pathways that regulate protein stability and function, including autophagy and ubiquitin-mediated processes that control cellular protein levels. The book progresses from foundational concepts to detailed analysis of how proteostasis defects drive major pathologies including cancer, neurodegeneration, chronic inflammation, and rare genetic disorders. Medical professionals, researchers, and advanced students will find this essential reference for understanding how imbalanced protein regulation contributes to disease development and progression. Part of the Advances in Experimental Medicine and Biology series (volume 1233), this Springer publication bridges basic molecular science with clinical applications, making complex proteostasis mechanisms accessible to those seeking to advance diagnosis and treatment strategies.

Key Features

Proteostasis and Disease covers autophagy, ubiquitin pathways, and protein homeostasis mechanisms that underlie health and pathological states.

Written by European PROTEOSTASIS network members, the book integrates current research on how defective protein regulation causes cancer, neurodegeneration, and inflammation.

Advances in Experimental Medicine and Biology volume 1233 progresses from basic introductory concepts to advanced clinical applications for medical professionals and researchers.

Springer's comprehensive reference addresses rare disease mechanisms linked to proteostasis failure, providing evidence-based insights for disease understanding and intervention strategies.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
10 April 2021
Listed Since
14 March 2021

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