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Springer Modified Nucleic Acids in Biology and Medicine - RNA Technologies

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Description

This comprehensive volume explores the critical role of modified nucleic acids in modern biology and medicine through 18 detailed chapters covering DNA modification, RNA bases, and circular RNA. The book examines how the chemical nature of DNA, RNA, proteins and lipids makes these macromolecules susceptible to modification and damage from endogenous and exogenous agents, including alkylation and oxidation that can disrupt cellular redox equilibrium and trigger inflammation and chronic disease. It provides in-depth analysis of therapeutic oligonucleotides and their diverse properties, alongside discussion of how DNA damage mechanisms drive mutagenesis. Essential for researchers, clinicians and students studying molecular biology, genetic engineering and therapeutic development, this Springer publication bridges fundamental biochemistry with practical medical applications in genetic medicine and treatment strategies.

Key Features

Covers 18 chapters on DNA modification, RNA modified bases and circular RNA with therapeutic applications in nucleic acid research.

Examines chemical modifications to DNA, RNA, proteins and lipids and their susceptibility to endogenous and exogenous damage.

Details therapeutic oligonucleotides and their distinct properties for medical and clinical applications.

Explores alkylation and oxidation effects on cellular redox equilibrium, inflammation pathways and chronic disease mechanisms.

Addresses DNA damage-driven mutagenesis and implications for medical genetics and therapeutic interventions.

Published by Springer as part of the RNA Technologies series for academic and professional medical education.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
07 June 2018
Listed Since
07 June 2018

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