Trinucleotide Repeats: Methods and Protocols: 2056 (Methods in Molecular Biology, 2056) - Image 1

£83.72

Humana Trinucleotide Repeats: Methods and Protocols: 2056 (Methods in Molecular Biology, 2056)

Name: Trinucleotide Repeats: Methods and Protocols: 2056 (Methods in Molecular Biology, 2056)
Brand: Humana
Price: 83.72 GBP
Availability: InStock

Mammals

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Description

This detailed book contains techniques to explore the unusual properties of the peculiar microsatellites known as trinucleotide repeats. Beginning with technical challenges raised by secondary structure-forming repeats and their propensity to contract and expand over time, the book continues with genetic screens in Saccharomyces cerevisiae, experimental systems to study trinucleotide repeat instability in human cells, dedicated experimental systems in appropriate cell types, as well as gene therapy approaches using the CRISPR-Cas family of endonucleases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Trinucleotide Repeats: Methods and Protocols serves as a valuable aid to experts and newcomers alike who seek to investigate this fascinating and ever-expanding field of study. From the Back Cover This detailed book contains techniques to explore the unusual properties of the peculiar microsatellites known as trinucleotide repeats. Beginning with technical challenges raised by secondary structure-forming repeats and their propensity to contract and expand over time, the book continues with genetic screens in Saccharomyces cerevisiae, experimental systems to study trinucleotide repeat instability in human cells, dedicated experimental systems in appropriate cell types, as well as gene therapy approaches using the CRISPR-Cas family of endonucleases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Trinucleotide Repeats: Methods and Protocols serves as a valuable aid to experts and newcomers alike who seek to investigate this fascinating and ever-expanding field of study.

Product Specifications

Brand: Humana
Format: paperback
ASIN: 1493997866
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Animal Sciences > Mammals
Domain: Amazon UK
Release Date: 05 October 2020
Listed Since: 10 September 2020

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Humana Trinucleotide Repeats: Methods and Protocols: 2056 (Methods in Molecular Biology, 2056)

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