ADARs and A-to-I Editing - Current Topics in Microbiology 353 - Image 1

£108.01

Springer ADARs and A-to-I Editing - Current Topics in Microbiology 353

Name: ADARs and A-to-I Editing - Current Topics in Microbiology 353
Brand: Springer
Price: 108.01 GBP
Availability: InStock

Immunology

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Description

This Current Topics in Microbiology and Immunology volume 353 provides comprehensive coverage of adenosine deaminases acting on RNA (ADARs) and their critical role in A-to-I editing mechanisms. The book establishes foundational knowledge about what ADARs are and how they function to influence gene expression and cellular processes. Beyond their enzymatic function of converting adenosine to inosine in double-stranded RNA substrates, ADARs operate as independent proteins with diverse biological roles. A-to-I editing directly affects base-pairing and RNA structure, with downstream consequences for translation, RNA splicing, viral replication, and microRNA and small interfering RNA silencing pathways. This Springer publication is essential for researchers, immunologists, and microbiologists seeking to understand ADAR biology and the molecular mechanisms underlying post-transcriptional RNA modification.

Key Features

The Springer volume explores ADARs as enzymatic catalysts that deaminate adenosine residues to produce inosine in double-stranded RNA substrates.

Current Topics in Microbiology volume 353 examines ADARs functioning as independent proteins with roles beyond their catalytic enzymatic properties.

This book analyzes how A-to-I editing affects RNA base-pairing and secondary structure, influencing translation efficiency and fidelity.

The volume covers impacts of ADAR-mediated editing on RNA splicing patterns, viral replication cycles, and miRNA and siRNA gene silencing mechanisms.

Product Specifications

Brand: Springer
Format: paperback
ASIN: 3642428177
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Immunology
Domain: Amazon UK
Publication Date: 26 January 2014
Listed Since: 05 December 2013

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Springer ADARs and A-to-I Editing - Current Topics in Microbiology 353

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