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Humana Poly(ADP-ribose) Polymerase: Methods and Protocols (Volume 780)

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Description

This comprehensive Methods in Molecular Biology volume explores Poly(ADP-ribose) Polymerases (PARPs), the abundant proteins regulating essential cellular processes including DNA repair, cell cycle control, genomic stability, and transcriptional regulation. PARPs mediate rapid cellular responses to environmental stress, infection, nutrition, and hormonal signals, making them critical for understanding fundamental cell biology. The book examines how PARP inhibitors can suppress tumour growth and proliferation in breast, ovarian, and prostate cancers, whilst providing researchers with essential protocols for studying PARP function. Designed for molecular biologists, biochemists, and cancer researchers, this volume offers practical methods and detailed protocols necessary for developing novel cancer treatment strategies and advancing understanding of PARP-mediated cellular mechanisms.

Key Features

Focuses on Poly(ADP-ribose) Polymerase methods and protocols for studying DNA repair and genomic stability in molecular biology research.

Covers PARP inhibitor applications in suppressing tumour growth in breast, ovarian, and prostate cancer cell models.

Provides detailed protocols for examining how PARPs regulate cell cycle control and transcriptional regulation processes.

Part of the Methods in Molecular Biology series (Volume 780), offering peer-reviewed techniques from Humana publishers.

Essential resource for researchers developing novel cancer treatment strategies through PARP-targeted therapeutic approaches.

Product Specifications

Brand
Humana
Format
hardcover
Domain
Amazon UK
Release Date
31 August 2011
Listed Since
08 April 2011

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