£113.94

Humana Hypoxia and Cancer - Drug Discovery and Development Book

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Description

Explore the complex relationship between oxygen levels and tumor progression in Hypoxia and Cancer: Biological Implications and Therapeutic Opportunities. This specialized text from the Cancer Drug Discovery and Development series examines how the imbalance between proliferating tumor cells and inefficient vasculature leads to hypoxia and anoxia in tumor tissues. Readers will gain a deep understanding of how intra-tumor hypoxia affects the biological behavior of cancer cells, contributing to therapy resistance and more invasive, metastatic phenotypes. The book covers the role of Hypoxia Inducible Factor 1 (HIF-1) as a master regulator of the transcriptional response to oxygen deprivation. This resource is designed for medical professionals and researchers looking to understand the hallmark of the malignant phenotype and the specific features of the tumor microenvironment.

Key Features

Examines the biological impact of hypoxia and anoxia caused by inadequate tumor vasculature.

Analyzes how oxygen deprivation leads to therapy resistance and invasive cancer phenotypes.

Provides detailed information on Hypoxia Inducible Factor 1 (HIF-1) as a transcriptional regulator.

Covers the essential role of hypoxia as a hallmark of the malignant phenotype.

Explores the characteristics of the tumor microenvironment in relation to oxygen levels.

Product Specifications

Brand
Humana
Format
paperback
Domain
Amazon UK
Release Date
23 August 2016
Listed Since
11 August 2016

Barcode

No barcode data available

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