£107.85

Springer Morphofunctional Aspects of Tumor Microcirculation - Springer

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Description

This Springer publication examines the structural and functional abnormalities of blood vessels within tumours, providing comprehensive insights into how these vessels differ fundamentally from normal vascular systems. The book explores the distinctive characteristics of tumour microcirculation, including their unusual leakiness, rapid growth and remodelling capabilities, and expression of unique surface molecules that facilitate tumour cell dissemination through the bloodstream. Detailed analysis covers the composition of these vessels-endothelial cells, mural cells, and basement membranes-whilst highlighting common features across different tumour types regardless of origin, size or growth pattern. The text addresses absent vascular hierarchy, formation of large-caliber sinusoidal vessels, and markedly heterogeneous vessel density alongside increased permeability that sustains the tumour microenvironment. This resource is essential for medical professionals, researchers, and healthcare practitioners specialising in oncology and internal medicine seeking to understand the complex relationship between vascular biology and tumour progression.

Key Features

Springer publication focusing on structural and functional abnormalities of tumour blood vessels and their role in cancer progression.

Comprehensive examination of how tumour microcirculation differs from normal vascular systems in composition and function.

In-depth analysis of endothelial cells, mural cells, and basement membrane structures within tumour vessels.

Explores distinctive mechanisms including unusual leakiness and rapid remodelling that enable tumour cell dissemination.

Addresses vascular hierarchy, sinusoidal vessel formation, and heterogeneous density patterns characteristic of tumour microcirculation.

Essential resource for oncology professionals and internal medicine practitioners researching the tumour microenvironment.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
29 September 2012
Listed Since
17 May 2012

Barcode

No barcode data available

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