Elsevier Modern Approaches in Drug Discovery Volume 610

Modern Approaches in Drug Discovery (Volume 610) is the latest release in the Methods in Enzymology series from Elsevier. This volume provides an in-depth look at new advances in the field of drug discovery. It covers essential topics including Target Identification and Validation, Cell Painting/High Content Imaging, and the use of chemical probes for Target ID. Readers can explore specialized subjects such as mining the microbiome for targets, data-driven approaches for diversity and drug-likeness, and affinity-based screening. The text also details fragment screening via X-ray, array-based approaches, and the processes for hit assessment, prioritization, and hit-to-lead assessment to improve drug-like properties. This volume serves as a comprehensive resource for professionals studying biochemistry and pharmaceutical development.