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PACLITAXEL BIOSYNTHESIS: Biosynthesis, Mechanisms of Action & Clinical Uses (Pharmacology, Research, Safety Testing and Regulation)

Amazon

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Price range: £68 - £70

Price levels: 2 different prices over 62 days

Description

Paclitaxel is an antimitotic drug that promotes microtubule polymerisation and produces sensitisation to radiation. Paclitaxel is a first-line drug for the treatment of non-small cell lung cancer and is used to treat metastatic ovarian cancer, breast cancer, head and neck cancer, and advanced cases of Kaposi's sarcoma. In this book, the authors discuss the biosynthesis, mechanisms of action and clinical uses of paclitaxel. Topics include paclitaxel resistance and overcoming strategies with structurally or functionally related drugs; molecular mechanisms that mediate resistance to paclitaxel in cancer; the biosynthesis of paclitaxel and its pharmaceutical application for cancer treatment; current status and clinical trials of paclitaxel-containing therapy for urothelial cancer; mesenchymal stromal cells used for carrying and delivering paclitaxel; and the role of paclitaxel in ovarian cancer.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
01 September 2013
Listed Since
29 June 2013

Barcode

No barcode data available

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