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Price distribution over 68 days • 1 price levels

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Most common price: £62 (68 days, 100.0%)

Price range: £62 - £62

Price levels: 1 different prices over 68 days

Description

Methyl α-D-glucopyranoside was easily prepared by the treatment of D-glucose with anhydrous methyl alcohol in the presence of hydrogen chloride at freezing temperature. Then N-acetylsulfanilylation of methyl α-D-glucopyranoside has been carried out by the direct method and afforded the 6-O-N-acetylsulfanilyl derivative in an excellent yield. In order to obtain newer products, the 6-O-N-acetylsulfanilyl derivative was further transformed into a series of 2,3,4-tri-O-acyl derivatives containing a wide variety of functionalities in a single molecular framework. The chemical structures of the newly synthesized compounds were elucidated by FTIR, Proton nuclear magnetic resonance spectroscopy, elemental and physicochemical properties analysis. All the newly synthesized D-glucose derivatives were tested for their in vitro antibacterial activity against some human pathogenic bacterial strains. The study revealed that a good number of compounds exhibited promising antibacterial activities. It is expected that the acylated derivatives of D-glucose may be considered as a potential source for developing new and better antibacterial agents against a number of pathogenic organisms.

Product Specifications

Format: paperback
ASIN: 6138938127
Category: Books > Subjects > Science, Nature & Maths > Chemistry > Organic Chemistry
Domain: Amazon UK
Release Date: 12 August 2020
Listed Since: 19 September 2020

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SYNTHESIS AND MICROBIAL SCREENING OF SOME GLUCOPYRANOSIDE DERIVATIVES: Approach to Pharmaceutical Uses

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