£87.62

Humana Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols: 988 (Methods in Molecular Biology, 988)

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Description

This Methods in Molecular Biology™ book offers protocols for glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. Covers glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complex characterization and PK/PD assays. Review From the reviews: “The book is intended as a reference manual of protocols and best practices for the practicing bench scientist. The authors do a marvelous job of covering a wide variety of tools and techniques and bringing them together in one volume. … This collection of protocols will find an audience with experimentalists in the biopharmaceutical industry as well as various academic labs. … Overall, I would strongly recommend this book … .” (Bibhash Mukhopadhyay, Frontiers in Pharmacology, September, 2013)“This book … useful as it details in one place the current state of art technologies and techniques for antibodies. I enjoyed reading the introductions to each chapter, which were accessible and gave an historical setting and overall aim for the methodologies that are set out in the chapter. … this book offers a good reference guide for those of us working in this area.” (Sian Estdale, BTS Newsletter – The British Toxicology Society, Issue 43, Winter, 2013) From the Back Cover Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins.  In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and cutting-edge, Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals.

Product Specifications

Brand
Humana
Format
paperback
Domain
Amazon UK
Release Date
23 August 2016
Listed Since
28 May 2016

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No barcode data available

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