Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena - Image 1

£102.79

Wiley Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena

Name: Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena
Brand: Wiley
Price: 105.99 GBP
Availability: InStock

Pharmacology

Price History & Forecast

Last 44 days • 44 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 44 days • 2 price levels

Days at Price

Current Price

Price Analysis

Most common price: £103 (29 days, 65.9%)

Price range: £103 - £106

Price levels: 2 different prices over 44 days

Description

A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to "fit-for-purpose" validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.

Product Specifications

Brand: Wiley
Format: hardcover
ASIN: 0470041382
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine > Pharmacology
Domain: Amazon UK
Release Date: 24 November 2009
Listed Since: 02 April 2007

Barcode

No barcode data available

Wiley Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Bioanalytical Aspects in Biological Therapeutics (Wiley on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods)

Wiley Targeted Biomarker Quantitation by LC-MS Textbook

Drug Metabolism in Drug Design and Development: Basic Concepts and Practice

Drug Development for Gene Therapy: Translational Biomarkers, Bioanalysis, and Companion Diagnostics

A Handbook of Bioanalysis and Drug Metabolism

Drug-Drug Interactions for Therapeutic Biologics

Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery: A Practical Guide for Pharmaceutical Scientists

Evaluation of Drug Candidates for Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology (Wiley Series in Drug Discovery and Development)

Mass Spectrometry in Medicinal Chemistry: Applications in Drug Discovery (Methods & Principles in Medicinal Chemistry)

Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad

Wiley Mass Spectrometry-Based Metabolomics Book - Wiley-VCH

Laboratory Guide to Enzymology

Wiley - Biological Drug Products: Development and Strategies

Handbook of Assay Development in Drug Discovery: 5 (Drug Discovery Series)

Regulated Bioanalytical Laboratories: Technical and Regulatory Aspects from Global Perspectives

Bioassay Techniques for Drug Development

Drug Metabolism and Pharmacokinetics: Frontiers, Strategies, and Applications

Translational ADMET for Drug Therapy: Principles, Methods, and Pharmaceutical Applications

Wiley - Contemporary Accounts in Drug Discovery and Development

Development of Therapeutic Agents Handbook: 8 (Pharmaceutical Development Series)

Drug Discovery Research: New Frontiers in the Post-Genomic Era

Basic Principles of Drug Discovery and Development

Detection and Quantification of Antibodies to Biopharmaceuticals: Practical and Applied Considerations

Wiley Analytical Testing for the Pharmaceutical GMP Laboratory