Exposure-Response Modeling: Methods and Practical Implementation (Chapman & Hall/CRC Biostatistics Series) - Image 1

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CRC Press Exposure-Response Modeling: Methods and Practical Implementation (Chapman & Hall/CRC Biostatistics Series)

Name: Exposure-Response Modeling: Methods and Practical Implementation (Chapman & Hall/CRC Biostatistics Series)
Brand: CRC Press
Price: 50.99 GBP
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Anthropology & Sociology

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Description

Discover the Latest Statistical Approaches for Modeling Exposure-Response Relationships Written by an applied statistician with extensive practical experience in drug development, Exposure-Response Modeling: Methods and Practical Implementation explores a wide range of topics in exposure-response modeling, from traditional pharmacokinetic-pharmacodynamic (PKPD) modeling to other areas in drug development and beyond. It incorporates numerous examples and software programs for implementing novel methods. The book describes using measurement error models to treat sequential modeling, fitting models with exposure and response driven by complex dynamics, and survival analysis with dynamic exposure history. It also covers Bayesian analysis and model-based Bayesian decision analysis, causal inference to eliminate confounding biases, and exposure-response modeling with response-dependent dose/treatment adjustments (dynamic treatment regimes) for personalized medicine and treatment adaptation. Many examples illustrate the use of exposure-response modeling in experimental toxicology, clinical pharmacology, epidemiology, and drug safety. Some examples demonstrate how to solve practical problems while others help with understanding concepts and evaluating the performance of new methods. The provided SAS and R codes enable readers to test the approaches in their own scenarios. Although application oriented, this book also gives a systematic treatment of concepts and methodology. Applied statisticians and modelers can find details on how to implement new approaches. Researchers can find topics for or applications of their work. In addition, students can see how complicated methodology and models are applied to practical situations.

Product Specifications

Brand: CRC Press
Format: paperback
ASIN: 036773804X
Category: Books > Subjects > Biography > Medical, Legal & Social Sciences > Anthropology & Sociology
Domain: Amazon UK
Release Date: 18 December 2020
Listed Since: 14 October 2020

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CRC Press Exposure-Response Modeling: Methods and Practical Implementation (Chapman & Hall/CRC Biostatistics Series)

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