Statistical Methods for Dose-Finding Experiments: 24 (Statistics in Practice) - Image 1

£82.56

Wiley Statistical Methods for Dose-Finding Experiments: 24 (Statistics in Practice)

Name: Statistical Methods for Dose-Finding Experiments: 24 (Statistics in Practice)
Brand: Wiley
Price: 83.89 GBP
Availability: InStock

Pharmacy - Dispensing

Price History & Forecast

Last 34 days • 34 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 34 days • 2 price levels

Days at Price

Current Price

Price Analysis

Most common price: £82 (26 days, 76.5%)

Price range: £82 - £84

Price levels: 2 different prices over 34 days

Description

Dose-finding experiments define the safe dosage of a drug in development, in terms of the quantity given to a patient. Statistical methods play a crucial role in identifying optimal dosage. Used appropriately, these methods provide reliable results and reduce trial duration and costs. In practice, however, dose-finding is often done poorly, with widely used conventional methods frequently being unreliable, leading to inaccurate results. However, there have been many advances in recent years, with new statistical techniques being developed and it is important that these new techniques are utilized correctly. Statistical Methods for Dose-Finding Experiments reviews the main statistical approaches for dose-finding in phase I/II clinical trials and presents practical guidance on their correct use. Includes an introductory section, summarizing the essential concepts in dose-finding. Contains a section on algorithm-based approaches, such as the traditional 3+3 design, and a section on model-based approaches, such as the continual reassessment method. Explains fundamental issues, such as how to stop trials early and how to cope with delayed or ordinal outcomes. Discusses in detail the main websites and software used to implement the methods. Features numerous worked examples making use of real data. Statistical Methods for Dose-Finding Experiments is an important collaboration from the leading experts in the area. Primarily aimed at statisticians and clinicians working in clinical trials and medical research, there is also much to benefit graduate students of biostatistics.

Product Specifications

Brand: Wiley
Format: Hardcover
ASIN: 0470861231
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Allied Health Professions > Pharmacy - Dispensing
Domain: Amazon UK
Release Date: 13 April 2006
Listed Since: 05 January 2007

Barcode

No barcode data available

Wiley Statistical Methods for Dose-Finding Experiments: 24 (Statistics in Practice)

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials: Handbooks of Modern Statistical Methods (Chapman & Hall/CRC Handbooks of Modern Statistical Methods)

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials: Handbooks of Modern Statistical Methods (Chapman & Hall/CRC Handbooks of Modern Statistical Methods)

Design and Analysis of Clinical Trials: Concept and Methodologies (Wiley Series in Probability and Statistics)

Success Probability Estimation with Applications to Clinical Trials

Statistical Issues in Drug Development (Statistics in Practice)

Dose Finding in Drug Development (Statistics for Biology and Health)

Bioequivalence Studies in Drug Development: Methods and Applications: 47 (Statistics in Practice)

Statistical Methods in Healthcare

Statistical Methods in Drug Combination Studies: 69 (Chapman & Hall/CRC Biostatistics Series)

Phase II Clinical Development of New Drugs (ICSA Book Series in Statistics)

Statistical Analysis of Designed Experiments: Theory and Applications (Wiley Series in Probability and Statistics)

Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials (Springer Series in Pharmaceutical Statistics)

Introduction to Statistical Methods for Clinical Trials (Chapman & Hall/CRC Texts in Statistical Science)

Clinical Trials: A Methodologic Perspective (WILEY SERIES IN PROB & STATISTICS/see 1345/6,6214/5)

Randomised Clinical Trials: Design, Practice and Reporting

Multiple Testing Problems in Pharmaceutical Statistics: 33 (Chapman & Hall/CRC Biostatistics Series)

Statistical Methods in Biomarker and Early Clinical Development

Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials (Springer Series in Pharmaceutical Statistics)

Management of Data in Clinical Trials (Wiley Series in Probability and Statistics)

Model-Assisted Bayesian Designs for Dose Finding and Optimization: Methods and Applications (Chapman & Hall/CRC Biostatistics Series)

The Theory of Response-Adaptive Randomization in Clinical Trials (Wiley Series in Probability and Statistics)

Clinical Trial Biostatistics and Biopharmaceutical Applications

Experiments: Planning, Analysis, and Optimization: 247 (Wiley Series in Probability and Statistics)

Case Studies in Innovative Clinical Trials (Chapman & Hall/CRC Biostatistics Series)