Elsevier Computer Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches (Drug Discovery Update)

Computer-Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches outlines the basic theoretical principles, methodologies and applications of different fundamental and advanced CADD approaches and techniques. Including information on current protocols as well as recent developments in the computational methods, tools and techniques used for rational drug design, the book explains the fundamental aspects of CADD, combining this with a practical understanding of the various in silico approaches used in modern drug discovery processes to assess the field in a comprehensive and systematic manner. Providing up-to-date, information and guidance for scientists, researchers, students and teachers, the book helps readers address specific academic and research related problems using illustrative explanations, examples and case studies, which are systematically reviewed. From the Back Cover <p>Complete overage of the fundamental and more advanced computer aided design approaches and techniques. </p> <p><i>Computer-Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches</i> outlines the basic theoretical principles, methodologies, and applications of different fundamental as well as advanced CADD approaches and techniques. Including information on current protocols as well as recent developments in the computational methods, tools and techniques used for rational drug design, the book explains the fundamental aspects of CADD, combining this with a practical understanding of the various in silico approaches used in modern drug discovery processes to assess the field in a comprehensive and systematic manner. Providing up-to-date, information and guidance for scientists, researchers, students and teachers, the book helps readers address specific academic and research related problems using illustrative explanations, examples, and case studies, which are systematically reviewed. Focusing on the current status and recent advances in computational tools, techniques and databases, guidance on experimental design in emerging therapeutic areas of interest using the latest CADD protocols and techniques is included. The information and resources embedded in the book will therefore be of benefit to beginners as well as experienced professionals. </p> <b> <p>Key Features</p> <ul></ul></b> <p> <li>Highlights <i>in silico</i> approaches to drug design and discovery using computational tools and techniques</li> <li>Detail’s ligand-based drug design and structure-based drug design in a comprehensive and systematic approach</li> <li><ul>Summarizes recent developments in computational drug design strategy as novel approaches of rational drug designing</ul></li></p> About the Author Dr. Mithun Rudrapal is presently working as Associate Professor and HoD at the Department of Pharmaceutical Chemistry, Rasiklal M. Dhariwal Institute of Pharmaceutical Education & Research (Affiliated to Savitribai Phule Pune University, Pune), Pune, Maharashtra, India. Dr. Rudrapal has been actively engaged in teaching and research in the field of Pharmaceutical and Allied Sciences for about 12 years. He has good number of publications (research papers and review articles) in peer-reviewed national and international journals of high repute to his credit. He has participated in many national and international seminars/ conferences, invited talks, workshops and refresher, short-term courses/ training programmes. He has authored a couple of books, more than twenty book chapters and is currently editing a number of books with reputed publishers including Elsevier, Wiley, T & F (CRC Press), Springer, Apple Academic Press, IntechOpen etc. Rudrapal is recipient of Gold Medal (T.U.), AICTE-GATE/UGC Fellowships, and National Awards (IPA, InSc.) for his academic excellence and research accomplishments. Rudrapal is a reviewer and on the editorial board of several journals with reputed Nati