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Wiley Metabolite Safety in Drug Development - Wiley Reference

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13 days 21 days · current 0 5 11 16 21 £106 £113 Days at Price

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Most common price: £113 (21 days, 61.8%)

Price range: £106 - £113

Price levels: 2 different prices over 34 days

Description

This comprehensive reference examines drug metabolism and metabolite safety during the development phase, providing essential guidance for pharmaceutical professionals. The book reviews analytical techniques and experimental designs critical for metabolite studies, covering methods including chirality analysis, species differences, mass spectrometry, radiolabels, and in vitro/in vivo correlation approaches. Real-world case studies illustrate lessons learned from industry experience, whilst regulatory perspectives from the US FDA and EMA ensure compliance with current standards. Target pharmacology and in vitro systems aligned to toxicity assessment are discussed throughout, making this an indispensable resource for drug development teams navigating metabolite characterisation and safety evaluation.

Key Features

Covers analytical techniques and experimental designs essential for conducting comprehensive metabolite studies in drug development.

Includes methods for chirality analysis, species differences assessment, mass spectrometry, radiolabels, and in vitro/in vivo correlation.

Features real-world case studies demonstrating lessons learned and practical applications from pharmaceutical industry experience.

Incorporates regulatory perspectives from both the US FDA and EMA to ensure compliance with current standards.

Addresses target pharmacology and in vitro systems designed for toxicity assessment during the metabolite safety evaluation process.

Product Specifications

Brand
Wiley
Format
hardcover
Domain
Amazon UK
Release Date
07 October 2016
Listed Since
15 May 2014

Barcode

No barcode data available

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