£107.98

Springer - The p53 Tumor Suppressor Pathway and Cancer 2

Name: Springer - The p53 Tumor Suppressor Pathway and Cancer 2
Brand: Springer
Price: 107.98 GBP
Availability: InStock

Diseases & Disorders

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Description

Explore the evolution of cancer research with The p53 Tumor Suppressor Pathway and Cancer: 2, published by Springer. This volume, part of the Protein Reviews series, provides a deep look into the history and development of p53 studies. Readers will trace the scientific journey of p53 from its early days when it was viewed as a viral antigen to its identification as an oncogene that works with activated ras to transform primary cells. The text explains how high levels of p53 expression in various tumorigenic cell lines initially shaped the understanding of its role in cell transformation. This book clarifies the historical context of the field, including how early research often relied on specific point mutants of p53. It serves as a comprehensive resource for those studying the biological mechanisms of tumor suppressors and the complex history of cancer cell line research.

Key Features

Part of the Protein Reviews series (Volume 2) for specialized scientific study.

Covers the historical transition of p53 from a viral antigen to an oncogene.

Provides context on how p53 expression levels relate to transformed and tumorigenic cell lines.

Examines the role of p53 in cooperation with activated ras during cell transformation.

Details the impact of early research methods involving p53 point mutants.

Product Specifications

Brand: Springer
Format: paperback
ASIN: 1489998799
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders
Domain: Amazon UK
Release Date: 27 November 2014
Listed Since: 29 November 2014

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Springer - The p53 Tumor Suppressor Pathway and Cancer 2

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