£107.27

Springer - Targeted Drug Strategies for Cancer and Inflammation

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Description
Explore the complex science of folate pathways and their role in metabolism and macromolecule synthesis with this professional resource from Springer. This text examines how antifolate drugs function, specifically focusing on those transported via the high capacity folate transporter, such as the reduced-folate carrier. Readers will gain insight into the mechanisms of dihydrofolate reductase inhibitors like methotrexate, as well as thymidylate synthase inhibitors including raltitrexed and pemetrexed. The content covers major medical advances from the last decade, such as the clinical approval of pemetrexed for treating mesothelioma and lung cancer. Additionally, the book discusses the scientific demonstration of how cell membrane-anchored folate receptors (FR) can be utilized in drug targeting. This book serves as a specialized resource for those studying oncology and the biochemical processes involved in cancer and inflammation treatments.

Key Features

Covers essential folate pathways used in metabolism and macromolecule synthesis.

Provides detailed information on antifolate drugs and their transport via the reduced-folate carrier.

Analyzes specific inhibitors including methotrexate, raltitrexed, and pemetrexed.

Discusses recent medical advances regarding pemetrexed for lung cancer and mesothelioma treatment.

Explains the role of cell membrane-anchored folate receptors in targeted drug strategies.

Product Specifications
Brand
Springer
Format
paperback
ASIN
1489988866
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain
Amazon UK
Release Date
01 October 2014
Listed Since
01 October 2014

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