£67.00

VDM Verlag Impact of Folate Absorption and Transport for Nutrition and Drug Targeting

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Last 82 days • 82 data points (No recent data available)

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£67.00 £65.49 £65.82 £66.15 £66.48 £66.81 £67.14 09 April 2026 29 April 2026 19 May 2026 08 June 2026 29 June 2026

Price Distribution

Price distribution over 82 days • 2 price levels

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Current Price
81 days 1 day · current 0 20 41 61 81 £66 £67 Days at Price

Price Analysis

Most common price: £66 (81 days, 98.8%)

Price range: £66 - £67

Price levels: 2 different prices over 82 days

Description
Food-drug interactions play an important role in the alteration of the pharmacokinetics as well as pharmacodynamics of drugs in vivo. The interaction of folic acid and tea was observed at the level of cellular uptake using Caco-2 cell monolayers. Remarkably, the clinical study with healthy human volunteers confirmed the interaction between tea and folic acid in vivo leading to lower bioavailabilities of folic acid. This outcome addresses the clinical consequences of folate deficiency caused by high intakes of tea. Folates have been employed as targeting moieties to tumor cells. Folic acid has a high affinity to folate receptors which are overexpressed in tumor cells. Therefore internalization of folic acid conjugated drugs or drug delivery systems are readily carried out via those receptors. A novel micelle platform consisting of amphiphilic DNA block copolymers was introduced for the first time for chemotherapeutic drug delivery, allowing the combinatorial testing of the drug carrier system. Folic acid conjugated nanoparticles act as a potential chemotherapeutic drug delivery system in in vitro assays.

Product Specifications
Brand
VDM Verlag
Format
paperback
ASIN
363901068X
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine > Pharmacology
Domain
Amazon UK
Release Date
25 April 2008
Listed Since
02 May 2008

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