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Springer Sequence-Specific DNA Binders for Mitochondrial Disease Therapy

Amazon

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£101.81 £94.82 £96.35 £97.87 £99.40 £100.92 £102.45 28 July 2026 15 August 2026 02 September 2026 20 September 2026 08 October 2026
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Description

This Springer Theses volume explores the development of sequence-specific DNA binders designed to treat mitochondrial diseases. The author provides comprehensive background on pyrrole-imidazole polyamides (PIPs) and mitochondrial disease research before presenting original research findings. The work introduces MITO-PIPs, novel compounds engineered to recognise specific sequences within mitochondrial DNA, alongside advanced techniques incorporating DNA alkylating reagents into PIP structures to enhance therapeutic efficacy. This scientific monograph combines foundational knowledge with cutting-edge discoveries in molecular biology and offers researchers and clinicians valuable insights into emerging approaches for addressing genetic mitochondrial conditions through targeted DNA binding mechanisms.

Key Features

Comprehensive coverage of pyrrole-imidazole polyamides (PIPs) and their role in mitochondrial disease research.

Presents MITO-PIPs, sequence-specific compounds developed to recognise and target mitochondrial DNA.

Details DNA alkylating reagent integration methods to enhance therapeutic potential of PIP-based treatments.

Springer Theses publication offering peer-reviewed research findings and methodology for scientific advancement.

Addresses molecular biology approaches to genetic mitochondrial disease therapy and treatment development.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
04 January 2022
Listed Since
02 November 2021

Barcode

No barcode data available

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