Springer Phosphoinositides I: Enzymes of Synthesis and Degradation

Explore the fundamental mechanics of cellular signaling and membrane organization with Phosphoinositides I: Enzymes of Synthesis and Degradation. Published by Springer as part of the Subcellular Biochemistry series (Volume 58), this text provides a deep look into the enzymes responsible for phosphoinositide turnover. Research over the last three decades has shown that these enzymes control vital physiological processes. This book examines their role in the initiation and progression of various conditions, including cancer, inflammation, neurodegenerative diseases, cardiovascular issues, and metabolic disease. Presented in two volumes, the content clarifies the mechanisms that control phosphoinositide conversion dynamics. The text follows the progression from phosphatidylinositol through the chain of lipid kinases that generate oncogenic lipids like phosphatidylinositol. This resource serves as a detailed guide for medical professionals and researchers studying the biochemical pathways that impact human health and disease progression.