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Springer Free Energy Calculations in Rational Drug Design - Springer

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Description

Free energy calculations represent the most accurate computational method available for predicting enzyme inhibitor binding affinities, and this comprehensive Springer publication covers the foundational theory and practical applications that emerged in the 1990s as computer power advanced. The book reviews state-of-the-art strategies designed to improve throughput and includes a dozen real-world examples demonstrating how free energy calculations were applied to design and evaluate potential drug candidates. Whether you are a pharmaceutical researcher, medicinal chemist, or computational biologist, this resource provides essential insights into one of the most reliable techniques for rational drug design, bridging the gap between theoretical computational chemistry and practical drug development workflows.

Key Features

Covers fundamental theory of free energy calculations and their role in predicting enzyme inhibitor binding affinities.

Features a dozen practical examples showing how free energy calculations were used to design and evaluate drug candidates.

Presents state-of-the-art computational strategies designed to improve throughput in rational drug design workflows.

Published by Springer, a leading authority in scientific and medical publishing.

Reflects advances in computer power from the 1990s that made these calculations practically applicable to drug design.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
31 December 2001
Listed Since
07 February 2007

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No barcode data available

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