Humana Thyroid Hormone Nuclear Receptor Methods and Protocols 1801

Explore the latest scientific developments in thyroid hormone research with this specialized volume from the Methods in Molecular Biology series. This book provides a deep look at T3 and T4 thyroid hormones and their nuclear receptors (TRs) from both conceptual and methodological perspectives. Readers will find detailed guidance on various research areas, including the use of engineered mice, human genetics of TRs, and the control of the hypothalamus-pituitary-thyroid (HPT) axis. The text also covers the importance of local thyroid hormone production and metabolism, as well as the pathological effects caused by TH/TR alterations. By including discussions on non-mammalian models, this volume offers a broad scope for researchers studying endocrine systems. This resource is designed to help scientists navigate complex methodologies and stay current with advancements in molecular biology and thyroid hormone studies.