£150.00

Humana Quantum Mechanics in Drug Discovery: 2114 Methods Book

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Description

Explore the practical applications of quantum mechanical (QM) methods in modern drug discovery with this specialized volume from the Methods in Molecular Biology series. This book provides a detailed look at how QM approaches address fundamental challenges in the pharmaceutical development process. Readers will learn how to use these methods to characterize protein-water-ligand and protein-protein interactions, which is essential for understanding molecular behavior. The text covers technical processes such as providing estimates of binding affinities, determining ligand energies, and identifying bioactive conformations. This resource is designed to assist in the refinement of molecular geometries and the scoring of docked protein-ligand poses. It also covers advanced topics including molecular similarity, structure-activity-relationship (SAR) analysis, and ADMET prediction. As part of the highly successful Methods in Molecular Biology series, this book serves as a technical guide for professionals working in drug design and molecular research.

Key Features

Covers QM applications for characterizing protein-water-ligand and protein-protein interactions to improve molecular understanding.

Provides methods for estimating binding affinities and determining ligand energies and bioactive conformations.

Includes techniques for the refinement of molecular geometries and scoring docked protein-ligand poses.

Explains methods for describing molecular similarity and conducting structure-activity-relationship (SAR) analysis.

Offers guidance on using quantum mechanical approaches for ADMET prediction in drug discovery workflows.

Product Specifications

Brand
Humana
Format
hardcover
Domain
Amazon UK
Release Date
04 February 2020
Listed Since
02 October 2019

Barcode

No barcode data available

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