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Humana Histone Deacetylases: Transcriptional Regulation - Cancer Drug Discovery

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Description

This comprehensive guide from Humana examines histone deacetylases and their role in gene expression regulation, a rapidly evolving field in cancer research. Leading investigators synthesise recent discoveries on histone acetylation mechanisms, detailing enzyme identification, enzymatic action pathways, substrate identification, and protein interactions. The book reviews solved enzyme structures both in isolation and bound to small molecule inhibitors, whilst exploring the biological functions of histone deacetylases across cellular processes. Essential reading for researchers, oncologists, and pharmaceutical scientists studying epigenetic regulation and developing targeted cancer therapeutics based on histone deacetylase inhibition.

Key Features

Histone deacetylases are examined as key regulatory mechanisms for controlling gene expression in cancer cells.

The book synthesises current knowledge on enzyme identification, enzymatic mechanisms of action, and substrate partnerships in histone acetylation.

Detailed analysis of solved enzyme structures both alone and complexed with small molecule inhibitors is provided.

Biological roles and cellular functions of histone deacetylases are thoroughly reviewed by leading investigators.

Cancer Drug Discovery and Development series positioning makes this essential for pharmaceutical researchers targeting epigenetic pathways.

Product Specifications

Brand
Humana
Format
hardcover
Domain
Amazon UK
Release Date
05 January 2006
Listed Since
05 February 2007

Barcode

No barcode data available

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