Humana G-Quadruplex DNA: Methods and Protocols - Vol 608

Explore the complex world of guanine-quartets with G-Quadruplex DNA: Methods and Protocols. This volume in the Methods in Molecular Biology series provides essential technical guidance for researchers studying the formation and dynamics of G-quadruplexes. Recent scientific findings indicate that stabilizing these structures in telomeric DNA can inhibit telomerase activity, opening new paths for the development of G-quartet-interacting drugs. This book serves as a practical resource for understanding how G-quartet-containing oligonucleotides act as potent aptamers against STAT3 and other transcription factors linked to oncogenesis. By providing a collection of detailed techniques, experts in the field offer the tools necessary to investigate these structures effectively. Whether you are researching molecular recognition or looking for ways to target specific biological processes, this text provides the foundational methods required for advanced study in biochemistry and molecular biology.