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Academic Press Regulators and Effectors of Small GTPases

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Description

Explore the fundamental mechanisms of cellular signaling with Regulators and Effectors of Small GTPases: Rho Family (Volume 406). Published by Academic Press as part of the Methods in Enzymology series, this volume provides a deep look into the Ras superfamily, which includes over 150 human members. This text covers the essential roles of Ras GTPases in cell proliferation, Rho GTPases in cytoskeleton regulation, and Rab GTPases in membrane targeting and fusion. It also examines the group of GTPases including Sar1, Arf, Arl, and dynamin that manage vesicle budding and fission. By understanding how these molecular switches function, researchers can gain insight into how their activities are controlled by regulatory molecules. The book details the processes involving guanine nucleotide exchange factors (GEFs) for GTP loading and GTPase activating proteins (GAPs) for GTP hydrolysis. This resource is a valuable addition to any biochemistry library, offering specialized knowledge on the biochemical pathways that drive cellular processes.

Key Features

Detailed coverage of the Ras superfamily including over 150 human members.

In-depth analysis of Rho GTPases and their role in regulating the cytoskeleton.

Examination of Rab GTPases involved in membrane targeting and fusion processes.

Technical information on Sar1, Arf, Arl, and dynamin regarding vesicle budding and fission.

Study of molecular switches and the regulatory molecules that control their activity.

Comprehensive look at GEFs for GTP loading and GAPs for GTP hydrolysis.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
25 February 2006
Listed Since
22 December 2006

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No barcode data available

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