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Academic Press - Regulators and Effectors of Small GTPases

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Description

Explore the complex world of the Ras superfamily with this specialized volume from the Methods in Enzymology series. This academic text provides a deep look into the Ras GTPases, which are essential to cell proliferation, and the various other members of this superfamily. Readers will gain knowledge on how these molecular switches function within biological systems. The book covers the vital roles of Rho GTPases in cytoskeleton regulation, Rab GTPases in membrane targeting and fusion, and specific GTPases like Sar1, Arf, Arl, and dynamin that manage vesicle budding and fission. Understanding the regulation of these proteins is key to biological research. This volume details how regulatory molecules control GTP loading through guanine nucleotide exchange factors (GEFs) and how they manage GTP hydrolysis via GTPase activating proteins (GAPs). This resource serves as a technical guide for those studying the mechanisms that control protein activity and cellular signaling.

Key Features

Comprehensive coverage of the Ras superfamily, including more than 150 human members.

Detailed analysis of Ras GTPases and their specific roles in cell proliferation processes.

In-depth information on Rho GTPases and their function in regulating the cytoskeleton.

Technical insights into Rab GTPases regarding membrane targeting and fusion mechanisms.

Exploration of Sar1, Arf, Arl, and dynamin GTPases involved in vesicle budding and fission.

Clear explanations of regulatory molecules like GEFs and GAPs that control molecular switches.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
11 June 2006
Listed Since
22 December 2006

Barcode

No barcode data available

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