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Elsevier Protein Misfolding Volume 118 - Advances in Protein Chemistry

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Description

Protein Misfolding, Volume 118, explores the comprehensive spectrum of diseases and disorders caused by protein misfolding, addressing degenerative and neurodegenerative conditions, cardiovascular disease, renal disorders, glaucoma, cancer, cystic fibrosis, and Gaucher's disease. This volume from Academic Press examines mass spectrometric approaches for profiling protein folding and stability, the critical role of biomembranes in protein misfolding, and how genetic and environmental factors interact to disrupt proteostasis and trigger protein misfolding diseases. The text also covers the formation of oligomers and large amorphous aggregates by intrinsically disordered proteins, providing researchers and healthcare professionals with essential insights into the molecular mechanisms underlying these complex conditions and their therapeutic implications.

Key Features

Protein Misfolding Volume 118 covers degenerative, neurodegenerative, cardiovascular, renal, and glaucoma diseases attributed to protein misfolding mechanisms.

Features mass spectrometric approaches for profiling protein folding stability and detecting protein structural changes in biological samples.

Examines biomembranes as key players in protein misfolding and aggregation processes relevant to disease pathology.

Discusses how genetic and environmental factors interact to disrupt proteostasis and initiate protein misfolding disease development.

Explores formation of oligomers and large amorphous aggregates from intrinsically disordered proteins in disease states.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
21 January 2020
Listed Since
12 July 2019

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