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Academic Press Protein Interactions in Drug Discovery Vol 121

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Description

Protein Interactions as Targets in Drug Discovery, Volume 121, provides essential insights into the design of therapeutics through both experimental and computational methods. Part of the Advances in Protein Chemistry and Structural Biology series, this volume focuses on the science of targeting protein interactions to advance medical research. Readers can explore specialized topics such as trends in structure-based drug design and the use of Supervised Molecular Dynamics (SuMD) to address the structural basis of binding. The text covers a wide range of technical areas, including the identification of potential inhibitors through computational analysis of protein-protein and protein-ligand interactions. Additionally, the book examines aromatic-aromatic interactions in protein-drug contexts. This volume serves as a comprehensive resource for professionals in biomedical engineering and medical research, offering a deep look into the structural mechanics required for modern drug discovery and therapeutic development.

Key Features

Covers both experimental and computational approaches to the design of new therapeutics targeting protein interactions.

Explores trends in structure-based drug design specifically focused on protein targets.

Details the use of Supervised Molecular Dynamics (SuMD) to address the structural basis of binding from fragment to peptide-protein interactions.

Provides methods for identifying potential inhibitors through computational analysis of protein-protein and protein-ligand interactions.

Includes technical research on aromatic-aromatic interactions in the context of protein-drug studies.

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