Hyperbaric Medicine: Principles and Clinical Practice

Hyperbaric Medicine: Principles and Clinical Practice is a comprehensive reference treatise that consolidates the author's previous publications in hyperbaric medicine into a single, fully integrated volume. Designed for physicians, healthcare professionals, researchers, educators, and hyperbaric practitioners, this textbook provides an extensive, evidence-based review of hyperbaric oxygen therapy (HBOT), encompassing both established indications and emerging clinical applications. The book is organized into three major sections: Part I: Fundamental principles of hyperbaric medicine, including physiology, oxygen toxicity, pharmacological effects, chamber technology, safety considerations, legal aspects, underwater medicine, and current perspectives on mild hyperbaric oxygen therapy (mHBOT) and soft chambers. Part II: Approved and widely accepted clinical indications, including arterial gas embolism, decompression sickness, carbon monoxide poisoning, chronic wounds, radiation-induced tissue injury, necrotizing infections, sudden sensorineural hearing loss, central retinal artery occlusion, avascular necrosis of the femoral head, and other conditions supported by contemporary hyperbaric practice. This section also reviews historical indications that have been abandoned because of insufficient scientific evidence. Part III: Emerging and investigational applications of HBOT, including neurological disorders, post-COVID syndrome, chronic pain syndromes, endothelial dysfunction, autoimmune diseases, mitochondrial medicine, sports medicine, reproductive medicine, aging biology, oncology, and other developing areas of clinical research. Particular emphasis is placed on the practical application of HBOT in daily clinical practice, including therapeutic decision-making, patient selection, oxygen dosing strategies, treatment planning, safety considerations, and protocol development. The text contains hundreds of structured tables, practical algorithms, therapeutic summaries, and evidence-based recommendations designed to facilitate rapid consultation and clinical implementation. Special attention is devoted to the pathophysiology of disease, mechanisms of action of hyperbaric oxygen, therapeutic rationale, and critical appraisal of the current scientific literature supporting each indication. This hardcover edition incorporates a unified table of contents, an extensive analytical index, and a highly structured chapter organization, making it suitable for long-term professional consultation, academic study, teaching activities, and institutional libraries. With more than 500 pages distributed across 56 chapters, this volume offers one of the most extensive single-volume reviews currently available in the field of hyperbaric oxygen therapy. It is intended both as a practical clinical guide and as a durable reference resource for specialists in hyperbaric medicine, wound care, rehabilitation medicine, emergency medicine, neurology, sports medicine, pain medicine, diving medicine, and related healthcare disciplines. A definitive reference for clinicians, educators, researchers, and healthcare professionals seeking a comprehensive and evidence-based resource in modern hyperbaric medicine.