Hyperbaric Medicine: Principles and Clinical Practice

Hyperbaric Medicine: Principles and Clinical Practice is a comprehensive reference work that brings together the author’s previous publications in hyperbaric medicine into a single, fully integrated volume. Designed for physicians, healthcare professionals, researchers, and hyperbaric practitioners, this textbook provides an extensive and evidence based review of hyperbaric oxygen therapy (HBOT), covering both established indications and emerging clinical applications. The book is organized into three major sections: Part I: Fundamental principles of hyperbaric medicine, including physiology, oxygen toxicity, pharmacological effects, chamber technology, safety considerations, and legal aspects. Underwater Medicine. Considerations on mHBOT and soft chambers. Part II: Approved and widely accepted clinical indications, such as arterial gas embolism, decompression sickness, carbon monoxide poisoning, chronic wounds, radiation-induced tissue injury, necrotizing infections, sudden sensorineural hearing loss, central retinal artery occlusion, avascular necrosis of the femoral head and other conditions supported by current hyperbaric practice. Review of indications previously considered but currently discarded due to lack of evidence. Part III: New and emerging applications of HBOT, with dedicated chapters on neurological disorders, post-COVID syndrome, chronic pain syndromes, endothelial dysfunction, autoimmune diseases, mitochondrial medicine, sports medicine, reproductive medicine, aging biology, oncology, and other developing fields of clinical research. Special emphasis is placed on the practical clinical use of HBOT, including therapeutic decision-making, patient selection, safety considerations, oxygen dosing strategies, and proposed treatment protocols applicable to daily clinical practice. The text incorporates numerous descriptive tables, structured therapeutic approaches, and practical summaries designed to facilitate rapid consultation and support clinical management across a wide range of medical conditions. Particular attention is given to pathophysiology, mechanisms of action, therapeutic rationale, and critical analysis of the current scientific evidence available for each indication. This edition includes a unified table of contents and a comprehensive subject index designed to improve accessibility, usability, and rapid topic retrieval for clinical practice, academic study, and professional reference. With its extensive clinical scope, structured therapeutic protocols, descriptive tables, and broad review of both established and emerging indications, this work represents one of the most comprehensive single volume clinical references currently available in the field of hyperbaric oxygen therapy. With more than 500 pages of detailed content organized across 56 chapters, this volume is intended as both a practical clinical guide and an academic resource for professionals involved in hyperbaric medicine, wound care, rehabilitation medicine, emergency medicine, neurology, sports medicine, pain medicine, and related specialties.