A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems - Image 1

Price loading...

Springer A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems

Name: A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems
Brand: Springer

Allied Health Professions

Price History & Forecast

No Price Data Available

Price history will appear here once data is collected from Amazon.

Price Distribution

No price data available for histogram

Description

The complexity of biological systems has intrigued scientists from many disciplines and has given birth to the highly influential field of systems biology wherein a wide array of mathematical techniques, such as flux balance analysis, and technology platforms, such as next generation sequencing, is used to understand, elucidate, and predict the functions of complex biological systems. More recently, the field of synthetic biology, i.e., de novo engineering of biological systems, has emerged. Scientists from various fields are focusing on how to render this engineering process more predictable, reliable, scalable, affordable, and easy. Systems and control theory is a branch of engineering and applied sciences that rigorously deals with the complexities and uncertainties of interconnected systems with the objective of characterising fundamental systemic properties such as stability, robustness, communication capacity, and other performance metrics. Systems and control theory also strives to offer concepts and methods that facilitate the design of systems with rigorous guarantees on these properties. Over the last 100 years, it has made stellar theoretical and technological contributions in diverse fields such as aerospace, telecommunication, storage, automotive, power systems, and others. Can it have, or evolve to have, a similar impact in biology? The chapters in this book demonstrate that, indeed, systems and control theoretic concepts and techniques can have a significant impact in systems and synthetic biology. Volume II contains chapters contributed by leading researchers in the field of systems and synthetic biology that concern modeling physiological processes and bottom-up constructions of scalable biological systems. The modeling problems include characterisation and synthesis of memory, understanding how homoeostasis is maintained in the face of shocks and relatively gradual perturbations,understanding the functioning and robustness of biological clocks such as those at the core of circadian rhythms, and understanding how the cell cycles can be regulated, among others. Some of the bottom-up construction problems investigated in Volume II are as follows: How should biomacromolecules, platforms, and scalable architectures be chosen and synthesised in order to build programmable de novo biological systems? What are the types of constrained optimisation problems encountered in this process and how can these be solved efficiently? As the eminent computer scientist Donald Knuth put it, "biology easily has 500 years of exciting problems to work on". This edited book presents but a small fraction of those for the benefit of (1) systems and control theorists interested in molecular and cellular biology and (2) biologists interested in rigorous modelling, analysis and control of biological systems.

Product Specifications

Brand: Springer
Format: hardcover
ASIN: 9401790469
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Allied Health Professions
Domain: Amazon UK
Release Date: 17 July 2014
Listed Since: 22 March 2014

Barcode

No barcode data available

Springer A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems

Price History & Forecast

No Price Data Available

Price Distribution

Description

Product Specifications

Barcode

Similar Products You Might Like

A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations

Springer Systems and Synthetic Biology Textbook

Systems Biology: An Integrated Platform for Bioinformatics, Systems Synthetic Biology & Systems Metabolic Engineering (Systems Biology - Theory, Techniques and Applications)

Feedback Control in Systems Biology

Synthetic Biology: Tools and Applications

Understanding the Dynamics of Biological Systems: Lessons Learned from Integrative Systems Biology

The Regulation of Cellular Systems

Feedback Control in Systems Biology

Biosystems Engineering II: Linking Cellular Networks and Bioprocesses: 121 (Advances in Biochemical Engineering/Biotechnology, 121)

Fundamentals of Systems Biology: From Synthetic Circuits to Whole-cell Models

Fundamentals of Systems Biology: From Synthetic Circuits to Whole-cell Models

Systems Biology for Signaling Networks: 01

The Regulation of Cellular Systems

Systems Biology: Mathematical Modeling and Model Analysis (Chapman & Hall/CRC Mathematical Biology Series)

Philosophy of Systems Biology: Perspectives from Scientists and Philosophers: 20 (History, Philosophy and Theory of the Life Sciences, 20)

INTRODUCTION TO METABOLIC AND CELLULAR ENGINEERING, AN (2ND EDITION)

Stem Cells: From Mechanisms to Technologies

Boundaries of a Complex World (Springer Series in Synergetics)

Control of Cell Fate in the Circulatory and Ventilatory Systems: 2 (Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems, 2)

Systems Biology of Cell Signaling: Recurring Themes and Quantitative Models

Systems Biology of Cell Signaling: Recurring Themes and Quantitative Models

Biomolecular Feedback Systems

Design and Analysis of Biomolecular Circuits: Engineering Approaches to Systems and Synthetic Biology

Design and Analysis of Biomolecular Circuits: Engineering Approaches to Systems and Synthetic Biology