Systems Biology: An Integrated Platform for Bioinformatics, Systems Synthetic Biology & Systems Metabolic Engineering (Systems Biology - Theory, Techniques and Applications)

Systems biology sits at the heart of new integrative paradigm in the 21st century, the book could gain an insight into (i) system structure and the mechanism of biological networks such as gene regulation, protein interactions, signalling, and metabolic pathways; (ii) system dynamics of biological networks, which provides an understanding of stability, robustness, and transduction ability through system identification, and through system analysis methods; (iii) system control methods at different levels of biological networks, which provide an understanding of systematic mechanisms to robustly control system states, minimize malfunctions, and provide potential therapeutic targets in disease treatment; (iv) systematic design methods for the modification and construction of biological networks with desired behaviours, which provide system design principles and system simulations for synthetic biology designs and systems metabolic engineering. This book not only describes the current developments in systems biology, systems synthetic biology, and systems metabolic engineering for engineering and biology researchers but also discusses challenges and future prospects for systems biology and the concept of systems biology as an integrated platform for bioinformatics, systems synthetic biology, and systems metabolic engineering. About the Author Professor Chen received the Ph.D degree from the University of Southern California in 1982. He was a professor at National Tsing Hua University and became a distinguished chair professor in 2014. He is a life fellow of IEEE. He has published about 300 journal papers in control, signal processing, communication, systems and synthetic biology. Dr. Hsu received his Ph.D degree form National Tsing Hua University in 2015.