Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis (Topics in Neuroscience) - Image 1

£62.66

Springer Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis (Topics in Neuroscience)

Name: Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis (Topics in Neuroscience)
Brand: Springer
Price: 62.66 GBP
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Neurology & Clinical Neurophysiology

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Description

There is now evidence that irreversible brain damage accumulates very early in the course of multiple sclerosis. This book reviews the main neurobiological, magnetic resonance imaging, and clinical aspects of the early phases of the dis ease. Mechanisms ofirreversible axonal damage and the role played by the inter action of glia and the axon are highlighted. In contrast to what was believed for a long time, the sufficient availability of oligodendrocyte precursor cells to promote remyelination in acute lesions has now been demonstrated. For reasons not understood, this remyelination process fails or does not start, particularly in the chronic stages ofthe disease. These findings emphasize the importance of the "milieu" changes induced by an inflammatory process in limiting remyelination. However, first indications are that part of this inflammatory process may have a neuroprotective effect. Pathological studies in multiple sclerosis have now clearly demonstrated that destructive processes may be followed by recovery phases in such a way that myelin may be morphologically and functionally reconstituted. These findings provide the rationale for early treatment and emphasize the importance of clinical trials in early multiple sclerosis. Early treatment is one of the most important aspects in multiple sclerosis today.

Product Specifications

Brand: Springer
Format: hardcover
ASIN: 8847001951
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Neurology & Clinical Neurophysiology
Domain: Amazon UK
Release Date: 06 February 2004
Listed Since: 15 December 2006

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Springer Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis (Topics in Neuroscience)

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