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£87.62

Springer Myelin Repair and Neuroprotection in Multiple Sclerosis

Name: Myelin Repair and Neuroprotection in Multiple Sclerosis
Brand: Springer
Price: 87.62 GBP
Availability: InStock

Neurology & Clinical Neurophysiology

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Description

This book covers the novel approach of myelin repair to restore conduction to demyelinated fibers, and to protect them against future loss, now emerging as a translational therapy for MS. Experts discuss what is needed to move toward clinical applications. Review From the book reviews: “The textbook discusses the cellular and molecular mediators of demyelination and regeneration of myelin support. It does a credible and well evidenced job at these two goals. National and international experts contribute to the dialogue. … I recommend this book to neurologists, neuroscientists, neurosurgeons … .” (Joseph J. Grenier, Amazon.com, August, 2014) From the Back Cover Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS). A number of research frontiers still exist in this challenging disease. The cause remains elusive, preventing breakthroughs in its prevention. The move towards oral immunomodulatory therapies has been a major advance, as has the finding of new genes linked to susceptibility that may open the door to new therapeutic approaches. However, a frontier that has been making significant strides in recent years has been that surrounding the neurobiology of myelin regeneration and axon protection: such have been the advances that clinical translation is on the cusp of being achieved. Two broad approaches to therapeutic enhancement of remyelination are envisaged: promoting endogenous remyelination by targeting cells present in the CNS, or, replacing lost myelinating cells from exogenous sources. Current research on oligodendrocyte biology, the pathology of MS, imaging of lesions and the biology of remyelination are paving the way toward opening this new translational frontier. Professor Duncan and Professor Franklin have assembled a broad group of experts in the fields of glial cell biology, neuropathology, radiology and clinical neurology to provide the background toward taking remyelination from experimented models into MS patients.

Product Specifications

Brand: Springer
Format: paperback
ASIN: 1489988408
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Neurology & Clinical Neurophysiology
Domain: Amazon UK
Publication Date: 19 September 2014
Listed Since: 20 September 2014

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Springer Myelin Repair and Neuroprotection in Multiple Sclerosis

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