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Una perspectiva clínica: Análisis de mutaciones EGFR en cánceres primarios de pulmón: EGFR en el cáncer de pulmón

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£67.00 £63.65 £64.99 £66.33 £67.67 £69.01 £70.35 09 July 2026 26 July 2026 12 August 2026 29 August 2026 15 September 2026

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Description

El cáncer de pulmón, o carcinoma broncogénico, incluye tumores malignos originados en las vías respiratorias o el parénquima pulmonar. Los principales factores de riesgo son el tabaquismo, la edad avanzada, la EPOC y la exposición a agentes carcinógenos como el amianto y el radón. Además, la susceptibilidad genética desempeña un papel importante, ya que entre el 10 y el 15% de los no fumadores desarrollan cáncer de pulmón, a menudo vinculado a fuertes antecedentes familiares. Los avances en la patogénesis molecular han demostrado que el cáncer de pulmón es una enfermedad heterogénea, impulsada por diversas anomalías moleculares. La progresión tumoral está influida por receptores como los receptores del factor de crecimiento epidérmico (EGFR), regulados por tirosina quinasas. Las terapias dirigidas contra estas mutaciones son ahora tratamientos de primera línea, mientras que la quimioterapia se utiliza para aquellos a los que les fallan las terapias moleculares. Este libro explora los factores demográficos y clínicos vinculados a la positividad de la mutación TK EGFR en pacientes con cáncer de pulmón en estadio avanzado (IV), basándose en la investigación de un centro de neumología intervencionista terciario de Pakistán.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
10 March 2025
Listed Since
11 March 2025

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