£108.01

Springer Molecular Pathogenesis of Colorectal Cancer

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£108 today · all-time low £108 (May 2026) · usually £108

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£110.54 £107.72 £108.34 £108.95 £109.57 £110.18 £110.80 21 May 2026 09 June 2026 28 June 2026 17 July 2026 06 August 2026

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9 days · current 5 days 0 2 5 7 9 £108 £111 Days at Price

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Most common price: £108 (9 days, 64.3%)

Price range: £108 - £111

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Description

This book identifies and characterizes targetable oncogenic pathways in colorectal cancer. It explores the current and future prospects for targeting these pathways therapeutically and presents emerging technologies for identifying new cancer related genes. From the Back Cover For more than two decades, colorectal cancer has served as the paradigm for the cooperative activity of oncogenes and tumor suppressor genes in cancer initiation and progression. The depth of molecular characterization for this disease is unparalleled, with specific mutations correlated to each histologic stage of progression from normal colon to malignant colorectal cancer. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. This book explores the past, present, and future of colorectal cancer genetics, with particular emphasis on how knowledge of the molecular pathogenesis of the disease leads to the development of novel therapeutic strategies. Individual chapters discuss general topics, such as genomic instability and inflammation, or else specific pathways, for example RAS, PI3K, and TGF-b, that play a role in colorectal cancer progression.

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