£71.00

Nuove combinazioni antimalariche per la malaria resistente alla clorochina: Plasmodium falciparum resistente alla clorochina in India e sviluppo di nuove combinazioni antimalariche

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£71.00 £67.45 £68.87 £70.29 £71.71 £73.13 £74.55 28 June 2026 17 July 2026 06 August 2026 25 August 2026 14 September 2026

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Description

La malaria colpisce 300-500 milioni di persone nel mondo e la mortalità varia da 1 a 2 milioni, i bambini in Africa sono i più sensibili. Con un vaccino non disponibile contro la malaria e farmaci di prima linea come la clorochina e gli antifolati che registrano una diffusa resistenza ai parassiti, la sfida del trattamento della malaria è un compito formidabile. Mentre la ricerca per scoprire nuovi farmaci è diventata essenziale, è diventato anche necessario identificare strategie terapeutiche a breve termine. Un approccio consiste nell'esaminare se i farmaci noti utilizzati per altre applicazioni possono essere utilizzati per trattare la malaria. Una seconda strategia consiste nel cercare composti naturali per l'attività antimalarica singolarmente o in combinazione. La terapia di combinazione ha assunto una notevole importanza nel contesto dei derivati dell'artemisinina essendo gli unici, testati, efficaci antimalarici rimasti nel paniere. Una terapia di combinazione con il derivato dell'artemisinina può prevenire la recrudescenza dovuta alla monoterapia, prolungare la durata del farmaco e forse anche ridurre il costo della terapia.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
07 March 2023
Listed Since
08 March 2023

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