Method Validation and Stability Analysis of Rifampicin by LC and LC-MS: Stability Studies of Rifampicin: Method Validation, and Characterization of Degradation Products by LC and LC-MS. - Image 1

£47.98

LAP Lambert Academic Publishing Method Validation and Stability Analysis of Rifampicin by LC and LC-MS: Stability Studies of Rifampicin: Method Validation, and Characterization of Degradation Products by LC and LC-MS.

Name: Method Validation and Stability Analysis of Rifampicin by LC and LC-MS: Stability Studies of Rifampicin: Method Validation, and Characterization of Degradation Products by LC and LC-MS.
Brand: LAP Lambert Academic Publishing
Price: 47.98 GBP
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This book presents a comprehensive study on the stability of rifampicin, a first-line anti-tuberculosis drug, through method development, validation, and characterization of its degradation products. It begins with an overview of tuberculosis, rifampicin's pharmacological profile, and the importance of stability-indicating methods in pharmaceutical quality control. Using HPLC and LC-MS techniques, the study optimizes chromatographic conditions and develops a validated stability-indicating method as per ICH guidelines. Forced degradation experiments under acidic, alkaline, oxidative, photolytic, and thermal stress reveal rifampicin's susceptibility to hydrolysis and other degradative pathways, with detailed characterization of degradation products. The validated method demonstrated accuracy, precision, linearity, robustness, and suitability for analyzing rifampicin in bulk and dosage forms. The work highlights the scientific and regulatory significance of stability testing in ensuring drug safety, efficacy, and quality throughout its shelf life, offering valuable insights for pharmaceutical research and development.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 6202433051
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine
Domain: Amazon UK
Release Date: 18 September 2025
Listed Since: 14 October 2025

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LAP Lambert Academic Publishing Method Validation and Stability Analysis of Rifampicin by LC and LC-MS: Stability Studies of Rifampicin: Method Validation, and Characterization of Degradation Products by LC and LC-MS.

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